High-throughput Chromosome Conformation Capture (Hi-C) enables the study of DNA interactions across the entire genome, generating high-resolution 3D chromatin structure maps and providing information on three levels: A/B compartments,

Reduced Representation Bisulfite Sequencing (RRBS) is an enzymatic-enrichment strategy that selectively captures promoter regions and CpG islands followed by bisulfite conversion and sequencing [3–5].

Targeted Bisulfite Sequencing (TBS) is a DNA methylation profiling technology that combines multiplex bisulfite-PCR capture with next-generation sequencing (NGS) at high depth [1-2].

Whole Genome Bisulfite Sequencing (WGBS) is the gold standard for DNA methylation research [1-2]. It employs bisulfite treatment to map the DNA methylation profile of the genome-wide with single-base resolution.

This kit optimizes the reagent components of the original CUT&Tag method, featuring exclusively designed elements such as a primary antibody binding enhancer and a DNA fragment release enhancer[1].